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When an unknown printer took a galley of type and scrambled it to make a type specimen book.

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Supplement Facts

Berberine (from Berberis aristata) – 400 mg
Alpha Lipoic Acid – 100 mg

Daily Dosage

Take 1 capsule twice daily with a meal, or as directed by a healthcare professional.

Enrich Your Daily Routine

What It Does

Berberine Synergy™ combines 400 mg of the plant alkaloid berberine (from Berberis aristata) along with 100 mg of alpha lipoic acid per capsule, in order to help support the management of healthy blood sugar levels and insulin sensitivity.* As downstream effects of these main actions, berberine may also help improve dyslipidemia, as well as other features of metabolic syndrome.

How It Works

There are multiple mechanisms behind berberine’s influence on blood glucose control and insulin sensitivity.5 In diabetics with damaged pancreatic islet function, berberine's antioxidant promoting activity protected islet cells and promoted insulin secretion. Other mechanisms involved include the upregulation of insulin receptor (InsR) expression via increased InsR mRNA and protein expression via protein kinase C activation, increased GLUT1 expression which stimulated glucose uptake, inhibition of retinol binding protein-4, and promotion of GLP-1 secretion.3 In another study of diabetic and myocardial necrotic induced mice, berberine treatment exhibited significant cardio-protective and anti-diabetic effects by restoring CPK-MB, HbA1c, and blood glucose levels while favorably modulating lipid levels.6

Daily Dosage

Take 1 capsule twice daily with a meal, or as directed by a healthcare professional.

Maximizing Its Performance

For optimal results, use consistently alongside a balanced diet that supports healthy blood sugar levels. Pair with regular physical activity and mindful carbohydrate intake to enhance metabolic support and overall effectiveness.

Why These Ingredients?

Berberine

A plant alkaloid that supports healthy blood sugar levels, insulin sensitivity, and metabolic function through multiple cellular pathways.

Alpha Lipoic Acid

Lipoic acid plays a key role in minimizing oxidative damage and decreases cellular decline that impacts major organ systems.

Patients and Experts Agree...

In a crowded market of supplements, RISE stands out by prioritizing science-backed formulations, ethically sourced ingredients, and rigorous third-party testing. Experience real results you can trust.

"I've evaluated countless supplement brands over my career, and most fall short of what I'd give my own family. Rise Complete is different; every formulation meets the clinical standard I require before I put anything in a patient's hands."
Scott Finkbeiner
Medical Director
"Most patients walk in frustrated from years of taking supplements that never moved their labs. A few months into Rise Complete, we start seeing biomarkers that finally reflect the work they're doing."
Stephanie Kotsur
NP